SEER-Medicare Analyses

We specialize in analyzing SEER-Medicare data, not only for solid tumors but also for lymphoma and leukemia (and eventually, myeloma). We have published our SEER Medicare work in a variety of journals, including Blood, BMC Cancer, Annals of Oncology, American Journal of Hematology, and Pharmacoeconomics. In addition, we have presented our findings at meetings for the American Society of Clinical Oncology (ASCO), American Society of Hematology (ASH), International Society for Pharmacoeconomics and Outcomes Research (ISPOR), and the San Antonio Breast Cancer Symposium (SABCS).

We created a summary of all of the SEER Medicare publications through 2020, which is available at our SEER Medicare Publications Summary page.  See below for selected publications using SEER-Medicare data.

Selected publications are listed below:

• Danese MD, Katz A, Cetin K, Chia VM, Gleeson M, Kelsh M, Griffiths, RI.  Treatment Patterns, Survival, and Hospitalization in Adult Patients with Acute Lymphoblastic Leukemia: An Observational Cohort Study Using SEER Medicare Data, Leuk Lymphoma. 2019 Aug;60(8):2015-2024. doi: 10.1080/10428194.2018.1555329. Epub 2019 Jan 11.
• Danese MD, Griffiths RI, Gleeson ML, Dalvi T, Li J, Mikhael J, Deeter R, Dreyling M.  Second-Line Therapy in Diffuse Large B-Cell Lymphoma (DLBCL):  Treatment Patterns and Outcomes in Older Patients.  Leukemia and Lymphoma.  2016. doi:  10.1080/10428194.2016.1228924
• Lowe KA, Danese MD, Gleeson ML, Langeberg WJ, Ke J, Kelsh MA.  Racial and Ethnic Variability in the Prevalence and Incidence of Comorbidities Associated with Gastric Cancer in the United States.  Journal of Gastrointestinal Cancer. 2016. 47:168-181
• Griffiths RI, Gleeson ML, Valderas JM, Danese MD. Impact of undetected comorbidity on treatment and outcomes of breast cancer. Int J Breast Cancer. 2014;2014:970780. doi: 10.1155/2014/970780. Epub 2014
• Griffiths RI, Lindquist KJ, O’Malley CD, Gleeson ML, Duryea JL, Valderas JM, Danese MD. Undiagnosed diabetes in breast, colorectal, lung, and prostate cancer: incidence and risk factors. ISRN Oncol. 2014 Mar 4;2014:607850. doi: 10.1155/2014/607850. eCollection 2014. PubMed PMID: 24729897; PubMed Central PMCID: PMC3960743
• Danese MD, Lindquist K, Doan J, Lalla D, Brammer M, Griffiths RI. Effect of Central Nervous System Metastases on Treatment Discontinuation and Survival in Older Women Receiving Trastuzumab for Metastatic Breast Cancer. J Cancer Epidemiol. 2012.
• Griffiths RI, Barron RL, Gleeson ML, Danese MD, O’Hagan A, Chia VM, Legg JC, Lyman GH. Granulocyte-colony stimulating factor use and medical costs after initial adjuvant chemotherapy in older patients with early-stage breast cancer. PharmacoEconomics. 2012;30(2):103-118.
• Griffiths R, Mikhael J, Gleeson M, Danese M, Dreyling M. Addition of Rituximab to Chemotherapy Alone as First-Line Therapy Improves Overall Survival in Elderly Patients with Mantle Cell Lymphoma. Blood, 2011;118(18):4808-4816.
• Griffiths RI, Lalla D, Herbert RJ, Doan JF, Brammer MG, Danese MD.Infused therapy and survival in older patients diagnosed with metastatic breast cancer who received trastuzumab. Cancer Invest. 2011 Nov;29(9):573-84.
• Lindquist, K., Danese, M. D., Mikhael, J., Knopf, K. B., Griffiths, R. I. Health Care Utilization and Mortality Among Elderly Patients With Myelodysplastic Syndromes. Ann Oncol. 2011 May;22(5):1181-8. Epub 2010 Nov 1.
• Danese MD, Griffiths RI, Gleeson M, Satram-Hoang S, Knopf K, Mikhael J, Reyes C. An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia.. Blood. 2011 Mar 31;117(13):3505-13. Epub 2010 Dec 29.
• Griffiths R, Gleeson M, Reyes C, Knopf K, Danese M. Survival in elderly follicular lymphoma patients who receive frontline chemo-immunotherapy. Am J Hematol. 2010 Dec;85(12):963-7.
• Griffiths R, Gleeson M, Knopf K, Danese M. Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL). BMC Cancer. 2010 Nov 12;10:625.
• M. Danese, C. O’Malley, D. Kim, K. Lindquist, M. Gleeson, R. Griffiths, D. Wyszynski. Comorbidities in Medicare patients with and without breast cancer. J Clin Oncol 27:15s, 2009 (suppl; abstr 6533).
• C. D. O’Malley, M. Danese, K. Lindquist, R. Griffiths, M. Gleeson, T. Einhorn, D. Wyszynski. Diabetes in elderly patients with breast cancer in the United States: An analysis of data from the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database. J Clin Oncol 27:15s, 2009 (suppl; abstr 11050).
• M. Danese, R. Griffiths, M. Gleeson, K. Knopf. Validating the Follicular Lymphoma International Prognostic Index (FLIPI) Using SEER-Medicare Claims Data. Blood (ASH Annual Meeting Abstracts) 2008 112: Abstract 872.
• Griffiths RI, Gleeson ML, Mikhael J, Danese MD. Cost and Cost-Effectiveness of Adding Rituximab to First-Line Chemotherapy for Follicular Lymphoma (FL) in Elderly Patients: An Observational Cohort Study Based on SEER-Medicare. J Cancer Epidemiol. 2012.
• Griffiths RI, Gleeson ML, Mikhael J, Dreyling M, Danese MD. Comparative Effectiveness and Cost of Adding Rituximab to First-Line Chemotherapy for Elderly Patients Diagnosed with Diffuse Large B-Cell Lymphoma. Cancer, 2012.
• Griffiths RI, Gleeson ML, Danese MD, O’Hagan A. Inverse Probability Weighted Least Squares Regression in the Analysis of Time-Censored Cost Data: An Evaluation of the Approach Using SEER-Medicare. Value Health. 2012 Jul;15(5):656-63. Epub 2012 Jun 22.
• Griffiths RI, O’Malley CD, Herbert RJ, Danese MD. Misclassification of Incident Conditions Using Claims Data: Impact of Varying the Period Used to Exclude Pre-Existing Disease. (Submitted).
• Griffiths RI, Gleeson ML, Valderas JM, Danese MD. Undiagnosed Comorbidity in Older Women with Breast Cancer: Incidence, Risk Factors, and Outcomes. (Submitted)
• Griffiths RI, Danese MD, Gleeson ML, Valderas JM. Epidemiology and Outcomes of Undiagnosed Diabetes in Older Women Diagnosed With Breast Cancer: An Observational Cohort Study Based on SEER-Medicare. (Submitted).
• Griffiths RI, Lindquist KJ, O’Malley CD, Gleeson ML, Duryea JL, Valderas JM, Danese MD. Undiagnosed Diabetes in Breast, Colorectal, Lung, and Prostate Cancer: Incidence and Risk Factors. (Submitted).